Corneal collagen cross-linking is a treatment that strengthens the cornea by using ultraviolet (UV) light and riboflavin (vitamin B2) to cross-link the collagen fibers, improving the structural integrity of the cornea. This procedure is most commonly used to treat keratoconus, a condition in which the cornea becomes thin and bulges outward, leading to vision distortion.

During the procedure, riboflavin drops are applied to the cornea, followed by exposure to UV light, which causes the collagen fibers to bond together and stiffen. This process helps to halt the progression of keratoconus and prevent further vision deterioration.

Corneal collagen cross-linking offers an effective solution for stabilizing the cornea, preserving vision, and reducing the need for a corneal transplant in patients with keratoconus.