Descemet's stripping endothelial keratoplasty (DSEK) is a type of partial corneal transplant in which only the inner layers of the cornea are replaced. This procedure is primarily used to treat endothelial diseases such as Fuchs' dystrophy, where the innermost layer of the cornea becomes damaged, leading to vision loss and corneal swelling.

DSEK involves the removal of the damaged endothelial layer, followed by the insertion of a thin graft of healthy donor tissue. This minimally invasive technique preserves more of the patient's natural cornea and has a faster recovery time compared to full-thickness corneal transplants.

DSEK offers excellent visual outcomes and helps reduce the risk of complications, making it a preferred choice for many patients with endothelial disorders.