Cryoplasty for peripheral artery disease (PAD) is a procedure that combines balloon angioplasty with cryotherapy (cold therapy) to treat blocked or narrowed arteries in the legs. During the procedure, a balloon is inflated to widen the artery, while cold therapy is applied to reduce tissue damage and improve long-term outcomes.

Cryoplasty has shown to be effective in treating PAD by not only restoring blood flow but also reducing restenosis (re-narrowing of the artery), thus improving patient mobility and reducing the need for repeat interventions.