Iliofemoral bypass is a surgical procedure used to bypass blockages or narrowing in the iliac and femoral arteries, which supply blood to the legs. The procedure uses a graft to reroute blood flow around the blocked arteries, restoring circulation to the legs and improving symptoms of peripheral artery disease (PAD), such as leg pain or ulcers.

Iliofemoral bypass is typically performed when PAD is severe, and the goal is to prevent complications such as tissue death or amputation by improving blood flow and reducing the risk of clots.